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by seph

FDA, Doctors See No Link Between Pancreatic Cancer, Byetta-type Drugs

2:32 am in Weight Problems by seph

Medical authorities see no increased risk between pancreatic cancer and Byetta-type pharmaceutical formulations, Medscape.com reports, mentioning initial reactions from certain doctors attending the National Institute of Diabetes, Digestive and Kidney Diseases (NIDDK) conference. Reactions from these doctors were given after listening to presentations of medical experts, among them Dr. Peter Butler who conducted a study linking these drugs to pancreatic cancer. The evaluation of various studies was hoped to allow concerned agencies to resolve the issue particularly for the Food and Drug Administration (FDA) and European Medicines Agency (EMA) who have been getting bad raps from the British Medical Journal on the handling of the Byetta and pancreatic cancer controversy.

 

There were many questions raised and there was much skepticism regarding the risk of cancer of the pancreas, according to Dr. Joseph Whitcomb, an expert of the pancreas and who acted as co-chairman of the NIDDK meeting. Dr. John Buse of the University of North Carolina School of Medicine also stated that no signal of pancreatic cancer can be detected based on the data from companies and other investigators. It would seem that the presentations of medical experts connected with drug manufacturers were given more credence by these doctors over the study conducted by Dr. Peter Butler.

 

 

Three points were raised by Dr. Whitcomb in assailing the clinical trials performed by the team of Dr. Butler. Pointed out as the first concern was the ages of the subjects for both the control group who were in their 30s and the patients who were found to have pancreatic cancer who were in their 50s. According to the doctor, the critical issue was in defining the appropriate control group and when the right control group is used, there is no evidence of increased risk.

 

The lesion found by Dr. Butler, the alpha-hyperplasia, is the wrong kind of cancer was asserted by Dr. Whitcomb. Pancreatic cancer is associated with glucagonoma, which was never discovered, and not hyperplasia.

 

The use of the weight of the pancreas in calculating hyperplasia was another point raised by the doctor. The results of the study may have been affected by this since, according to Dr. Whitcomb, the pancreas of those with diabetes and in the elderly people tends to shrink.  

 

On the other hand, both doctors gave weight to the claims of Dr. Alan Moses, the global chief medical officer of Novo Noridisk and Dr. Sam Enger, the medical expert from Merck. An analysis based on a five-year study was presented by Dr. Moses which showed that the risk of pancreatic cancer was 0.7 compared to other diabetes drugs such as the widely-used metformin. In the study conducted by Merck using 14,000 patients from 25 randomized clinical trials, it was concluded that there was no increased risk of pancreatic cancer with use of their medications.

 

Based on their reactions, even the Food and Drug Administration (FDA) would seem to agree with the position of both doctors which suggests that no signal of pancreatic cancer can be detected. This was based on its own evaluation using different studies and independent of those conducted by pharmaceutical companies. Vigilant monitoring of the issue as well as supporting long-term studies on the subject have been assured by the FDA perhaps to assuage everyone concerned and to be on the safe side.

 

It is unfortunate that the side of Dr. Butler was not aired to answer these questions raised by the two doctors who incidentally have relationships with drug manufacturers. Reactions of the two doctors on the recommendations of the Institute of Safe Medication Practices (ISMP) and on the results of other studies such as the one conducted by Dr. Singh of the John Hopkins University would also be very welcomed by the millions of people affected with diabetes.

 

References:

medscape.com/viewarticle

nursingtimes.net/home/behind-the-headlines/diabetes-drugs-may-be-linked-to-pancreatic-cancer/

by seph

Handling Diabetes Is Difficult Without Having This Great Advice

3:17 pm in Weight Problems by seph

Diabetes has become the most significant global health threats. More and more people are diagnosed every day. This short article offers a wealth of information which is of special importance to anyone who has ever been clinically determined to have diabetes or knows another individual that is dealing with the condition. Read on for tips and guidelines in relation to various topics relevant to diabetes.

It may be challenging and discouraging if your little one is diagnosed being a diabetic, but you will need to stay strong and assist them to through it. You child can have a long and fulfilling life because there are tons of medications which make it easy to manage diabetes. The present oldest living diabetic is 90 years of age! This means that he was living in a time when all the current medical knowledge we now have wasn’t available!

You ought to test yourself for apnea if you suffer from diabetes. If apnea is a problem for yourself, then seek treatment when you can to keep up a healthy and active life.

Many items on store shelves have this ingredient, so be sure you’re choosing products without this prior to deciding to place them in your cart. Most soda drinks contain high fructose corn syrup, but so does ketchup, check the labels. Should you be Canadian, this ingredient is called “glucose/fructose.”

If hypoglycemia is an issue, be sure to carry some form of sugar food with you always, like gum. A hypoglycemic attack can happen whenever you want, so it is vital that you will be always prepared. This is certainly even more important when you skip breakfast, on account of your body is going to be craving sugar.

You don’t need to sign up in a gym. Exercise free of charge by walking or jogging. This will aid with weight loss and overall fitness. Try doing chin ups around the jungle gym, or lift weights using canned goods or fabric bags full of heavy items.

It can be hard for diabetics to face up to snacking on junk foods. Without exceptions avoid this temptation, and try a fruit, or perhaps a veggie.

Watching the foods you eat is of critical importance once you have diabetes. Different food affect your blood sugar levels differently, so you need to closely monitor your food intake. Large meals require large insulin injections but smaller meals require smaller insulin injections. If you view your meals, you are able to actively manage your sugar levels.

Being identified as having diabetes doesn’t have to be the worst thing ever. Apply these guidelines for your life to control your trouble and are available on top with your fight against diabetes.

Grace Jackson is a writer that prefers things linked with wellness along with healthy eating. For more about health and nutrition click here.

by seph

Experiencing Difficulty Managing Your Diabetes? Try These Helpful Tips

5:16 pm in Weight Problems by seph

Have you been certain of what you should be eating if you have diabetes? Are you aware the quantity of sleep you should have, or simply how much exercise you require? Utilize this article’s guidelines to help you combat this tough condition.

Try to keep a tight schedule to be able to simplify your daily life and let the body to get accustomed to normal cycles. Maintain your testing supplies and medicines in one location, and ensure you depart them there when you finish your routine. Make testing a routine and practice it simultaneously and in the same manner which means you never miss a step.

In case you are diabetic, you need to learn to indulge in a wholesome manner. You almost certainly don’t must avoid sweets altogether. When your blood sugar levels are in order, eating desserts occasionally is no problem. If you eliminate some carbohydrates through your meals, you will get more room to consume dessert.

Remember to keep sugary gum or some other kind of sugar that is quick to seize and consume readily available when you are hypoglycemic. Hypoglycemia attacks can happen anywhere, and it is crucial that you might be prepared for one. This is certainly specially the case when breakfast is skipped, because the body is already seeking sugar.

Many online pharmacies offer steep discounts on popular diabetes medications. Sometimes they may even deliver for you personally every month.

Diabetics must have their eyes checked frequently in order to avoid serious vision disorders, so be sure you address any concerns or problems with your health care provider. Many eye problems could be brought on by diabetes, for example cataracts, glaucoma, and diabetic retinopathy. You must attend to these issues without delay to prevent possible vision loss and/or blindness.

In case you have diabetes, you should focus on the foods you eat. Different foods will all have different effects on the blood sugar levels, so be careful when selecting meals and snacks. Larger meals will demand larger insulin injections, while smaller meals require less. When you are proactive with the meals, it will be easy to appropriately manage your blood glucose levels.

Diabetics should consume moderate portions, on a regular basis — as frequently as six times every day, as opposed to three. Eating often through the day helps maintain your blood sugar levels at stable levels. Besides, eating more regularly should enable you to lessen your snacking.

As you can tell, there is lots to know about managing diabetes. It may be frustrating to reside daily with diabetes. Apply everything you now know so that you can start splitting up those clouds.

Elijah Mercer is an article writer who delights in every little thing linked with wellness as well as diet. Read more on nutrition here.

by seph

Understanding Why Diabetes Affects Your Sex Life

2:02 am in Weight Problems by seph

Diabetes-associated damages run in many directions, from the nerves at one point to the blood vessels, sugar production capacity, and emotion controls, in another. Based on various clinical studies, medical experts have long acknowledged that this medical condition may impact significantly on a man’s sexual health. Long before any long-term complications or damages may surface, a person suffering from diabetes may encounter sexual problems like erectile dysfunction or a decline in sexual desire.

 

The following are the causes of this complication which may affect over 50 percent of men suffering from diabetes:

 

 

Damage to Nerves

Due to the damage caused by your condition to the nerves, signals from the brain consisting of sexual desire may not be sent properly to your body and sexual organ. Responsible for the nerve damage is the high level of blood sugar which results to the failure to provide the necessary oxygen and nutrients thereby affecting the proper functioning of the cells. Although you may be emotional aroused, your sexual organ will not be able to receive any sensation and therefore no response provided.

 

Blood Vessel Damage

Blood vessels may also be damaged by a high level of blood sugar which may restrict the flow of blood due to the narrowing or hardening of the blood vessels. Inadequate blood going to the penis may result to the inability to achieve or sustain erection since a man’s erection is brought about by the flow of blood.

 

Lack of Nitric Oxide

The inability to produce nitric oxide is another effect of poor blood sugar. This chemical, which is released in the penis, is very vital in providing erections for the male. Nitric oxide is very vital in providing erections for the male when released in the penis. There might not be enough blood to close off the veins since this may be prevented by the lack of nitric oxide. The blood may then flow back resulting to making the penis flaccid when the quantity of blood required to sustain an erection is not maintained.

 

Mental or Emotional Factors

Failure to achieve erection may have severe implications on your mental condition. You may become impotent when your fear of failure makes an impact on your psyche. Body chemicals which may dampen sexual performance may be produced when a person is under stress.

 

Distressing this might be, you should not be worried since there are some things you can do to address this problem What is important is to control your blood sugar level through lifestyle changes such as following the proper diet, engaging in physical activities, quitting smoking, and maintaining the ideal body weight.

 

Your doctor may also prescribe medications for the management of your diabetes condition. You should take an active role when prescribed with medications by knowing the benefits and side effects of these medicines. Diabetes medicines such as Byetta and other brands under the same class have been alleged by patients to cause severe complications. These complaints have resulted to litigations such as the Byetta lawsuits. You may visit byettalawsuits.us for more information regarding this matter.

 

References:

diabetes.webmd.com/news/20100827/diabetes-has-an-impact-on-sex-life

healthpages.org/self-care/sex-diabetes/

 

onlymyhealth.com/how-does-diabetes-affect-sex-life

by seph

Aerobics, Resistance Training Effective In Managing Diabetes, Study Shows

1:02 am in Weight Problems by seph

Diabetic patients who combine aerobic exercise with resistance training to realize an increase in fitness level and a reduction of weight were found to have experienced significant improvements in their conditions, according to a very recent study published in the magazine Diabetic Care. Patients were reported to be 2.81 times more likely to realize lower levels of glucose and a significant decrease in the use of drugs to manage their ailments after reducing their weights and increasing their fitness level, according to the leader of the research group, Dr. Timothy S. Church of Pennington Biomedical Research Center.

 

A total of 201 subjects were included in the study who were suffering from type 2 diabetes and came from different demographics. Those who participated in the study were patients aged 30 to 75 years with the mean at 58 years. Participants may be considered as obese, with an average body mass index (BMI) of 35 and described as having poor fitness levels.

 

Subjects were divided into three groups with one group doing either the aerobic exercise or resistance training, another group doing both exercise, and the third acting as a control group. The aerobic exercise of the first group consisted of brisk walking for 140 minutes per week on an inclined treadmill at a maximum heart rate of 50 to 80 percent while resistance training involved basic workout at the same standards. The group that was assigned to do both exercises spent 110 minutes per week doing brisk walking and 30 minutes per week for the strength training.

 

Glucose levels,  weight, body mass index, waist circumference, body fat, measures of fat mass, leg muscle strength, estimated effort expended during exercise or the estimated metabolic equivalents of tasks (METS) were the criteria used in assessing the respondents after the nine-month study period. The dual energy X-ray absorptiometry (DEXA) was used in determining the participant’s body fat composition.

 

The authors highlighted two aspects which had huge impact on glucose levels although there were a number of criteria used in the evaluation of results. Considered to have the most impact on glucose levels were the reduction of body fat as manifested in the waist circumference and fitness level which was determined by how long a patient performed the exercise on the treadmill.

 

By using different sets of exercises in the methodology, this study differs from previous researches of the same nature. Although similar in some degree, other studies use only one type of exercise which is usually aerobic and in some cases, a combination of different factors such as diet and behavioral changes are used.

 

Indeed, exercise on its own may really be very beneficial to a person suffering from type 2 diabetes. A more substantial improvement may be realized if other measures such as diet, healthy lifestyle, and other conservative methods are incorporated.

 

This may benefit a patient since the need for medications may be eliminated, which may also spare the patient from unwanted risks in light of the numerous complications resulting from the use of certain type 2 diabetes medicines. Numerous litigations such as the Byetta lawsuits have been filed across the country as a result of the complications suffered by patients. For more information about this, you may visit byettalawsuits.us.

 

References:

medscape.com/viewarticle/

ncbi.nlm.nih.gov/pmc/articles/

by seph

Results Of Studies On Byetta Complications Alarm FDA

7:32 pm in Weight Problems by seph

 

Using the new findings of academic researchers on the possible risks associated with the use of a class of drugs called incretin, which includes the Byetta injectable, the Food and Drug Administration (FDA) will conduct a comprehensive evaluation, according to their statement released in March this year. These researches included one which was undertaken very recently and determined that the continued use of Byetta may increase the risk of thyroid cancer.

 

Additional data such as details of the study and tissue samples have already been requested by the agency which it may use for further evaluation. Forum for this evaluation will be the  National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and National Cancer Institute’s (NCI) Workshop which the FDA will participate this coming June. The agency is hoping to come up with conclusions and recommendations regarding this issue after sharing and gathering relevant inputs during the workshop.

 

 

Concerned sectors are hoping that the FDA will be able to come up with more decisive actions to address this serious and growing problem. Confronted with the same issue in previous years, the FDA’s actions consisted of issuing notices to healthcare providers and ordering manufacturers to amend their labels by indicating possible risks involved in the use of these medications. Adverse reports at that time indicated that the use of Byetta was associated with the increase in complications affecting the pancreas and other important organs.

 

More serious problems resulting from the continued use of Byetta medications have been pointed out by the latest studies of these different research groups. The Institute for Safe Medication Practices, using the adverse reports provided by the FDA, reported that in a span of one year, over 105 cases of pancreatic cancer were observed as compared to only two patients who were using a different type of diabetes medication. An earlier research made by the University of California in Los Angeles where it reported an increase in pre-cancerous cellular changes by as much as 40 percent is supported by this latest study by ISMP.

 

The continued use of Byetta and other drugs in the same class may increase the risk of a patient in developing thyroid cancer, according to a report in the medical journal Gastroenterology, based on the study conducted by Dr. Peter Butler. The same negative findings, based on a different study, were also reported in the GI & Hepatology News, which is the official newsletter of the American Gastroenterological Association (AGA).

 

References:

medicalnewstoday.com/articles

fda.gov/Drugs/DrugSafety/ucm

nlm.nih.gov/medlineplus

 

by seph

Diabetes Mellitus: What You Need To Know

8:46 am in Weight Problems by seph

Diabetes mellitus is a lifelong condition characterized by high levels of sugar in the systemic circulation. It has two kinds, namely, type 1 diabetes because of the loss of insulin-producing cells in the pancreas, which in turn brings about insulin deficiency, and type 2 diabetes that is brought about by insulin resistance or cellular inability to make use of insulin. The occurrence of diabetes is growing quickly worldwide, but most drastically in developed countries. As of 2010, it is estimated that 285 million individuals all over the world have diabetes, with Type 2 DM comprising 90 percent of these cases. It is estimated that by 2030, this number will grow by a 100 percent.

Causes of diabetes

Type 1 diabetes

This kind of diabetes is partly inherited, and it often shows up after an infection. In type 1 DM, the person’s immune system attacks and eliminates insulin-producing cells, leaving the body with no or minimal insulin. This kind of diabetes is unrelated to lifestyle, and it can come about as early as childhood.

Type 2 diabetes

This form of diabetes is a lifestyle disease, and it is strongly associated with obesity, however, not all type 2 DM patients are obese. Genes can also predispose you to have type 2 diabetes, and environmental factors activates this predisposition. Certain diseases, polycystic ovary syndrome for example, and several medicines, like glucocorticoids, can raise the risk for diabetes.

What are the symptoms of diabetes?

Both types of diabetes can manifest the same signs and symptoms. Diabetes sufferers often experience excessive thirst and consequently frequent urination, frequent and intense hunger and fatigue due to cellular starvation, and recurring infections. Inexplicable weight loss may also be experienced, but not in all cases. Poorly managed diabetes can also result in microvascular changes, which can cause vision changes, delayed wound healing especially in the legs, and reduced sensation in the hands and feet, which increases their chance of being wounded without their knowledge. Tap here to discover more about Cases of diabetes.

Treatment

Currently, there are no proven cures yet for diabetes, but it can be managed effectively and complications can be prevented by means of medications, just like insulin and oral hypoglycemics, and lifestyle changes, which include observing a healthy diet and raising physical activity. Blood sugar monitoring and routine check-ups with a health care provider are also essential to monitor the effectiveness of diabetes management as well prevent or detect complications. For diabetes that is hard to control, a pancreas transplant is also a solution, but only used as a last resort. It is also vital that you quit smoking and restrict taking in of alcohol because these can accelerate the development of complications.

by seph

Reasonable Blood Glucose Levels – Normal Range Blood Sugar Levels

8:33 pm in Weight Problems by seph

Are you presently diagnosed with diabetes or pre-diabetes? If yes, then for sure your prime concern must be to sustain adequate blood sugar levels. In the event you or a person you love is dealing with the issue of blood glucose control then you need to continue reading.

What’s Blood sugar? First it’s important to have a fundamental comprehension about sugar. Glucose can be a sort of glucose which flows in the body of man. It enters the physique with the foods we consume in the kind of carbohydrates. A person can control and maintain adequate blood sugar levels by using glucagons and blood insulin hormone. These bodily hormones are made by the pancreas. The issue begins to obtain even worse if pancreas doesn’t produce needed quantity of insulin to keep the blood sugar in manage.

Adequate blood sugar levels are generally in between 70mg/dL and 150 mg/dL. The ranges of glucose in blood differs broadly and it depends on different elements. These contain particular time of the day, previous meal you ate and also the physical activity. There are harmful blood glucose levels also. These ranges might be either above or perhaps beneath the range. Some indicators of higher glucose level in blood contain irritability and not enough concentrate and energy. Occasionally even someone loses its consciousness when the sugar lowers below the normal range.

If the degree of glucose in blood vessels is more than 150 mg/dL then a person is deemed to be hyperglycemic. This condition is typically termed substantial blood sugar. If an individual is affected by persistent low ranges of sugars in bloodstream the situation is termed hypoglycemic. Each are harmful blood sugar levels. Prolonged deviation from the regular range blood sugar level outcomes in serious injury to kidneys, eyes along with other body organs. It is important to take steps to manage the situation.

Subsequent are the tests performed for managing the degree of glucose in blood.Fasting Blood glucose Test: This check is completed to evaluate the degree of glucose right after a quick. This fast is typically 8 hours lengthy. It really is advised to take this test as initial factor in the am. In the event the final results of the check fall under 70 mg/dL and 99 mg/dL then the patient is considered to be in the regular assortment.two Hours Postprandial Blood Check: This test examines the degree of glucose in blood usually 2 hours following the meal. In the event the final results of this check come in the range of 70 mg/dL and 99 mg/dL then it is regarded as that patient have an reasonable blood glucose degree.

Random Blood sugar Check: The degree with the sugar in blood is tested all through the day regardless of the food timings. The typical blood sugar ranges for this check are within 70 mg/dL and 135 mg/dL.Oral Glucose Tolerance Test: This check is performed following giving the individual a glucose drink. The aim of this test is usually to verify the response of the bloodstream when a large level of sugar is discharged in the blood.

Learn much more about the specifics of Blood Sugar Levels and discover the tricks to achieve Normal Blood Sugar Levels. I’ve pointed out right here tips and tricks with all the assist that I’ve said “good-bye” to Diabetes; so you can do the identical.

by seph

Learn How To Reverse Type 2 Diabetes

12:45 pm in Weight Problems by seph

First, let’s draw the line between reversible and curable. Diabetes Mellitus is a reversible illness, but it is not curable. Diabetes is a medical condition of elevated blood sugar causing different signs and symptoms affecting the cardiovascular system, kidneys, nerves, liver, and other vital organs of the body. It turns into reversible when an individual is thought to be liable to buying the illness but then doesn’t end up having the disease Novitec USA as a result of he was capable of manage his danger factors. You probably have been identified to have a household history of diabetes, obese, from Hispanic descent, a girl, and other threat components for diabetes, you continue to can reverse diabetes.

Below are some key points to think about in the event you consider you’ve or at risk of having type 2 diabetes:

    * Have common blood sugar tests. Normal blood sugar is 70-eighty mg/dl earlier than meals and beneath one hundred twenty mg/dl one or two hours after a meal. There are totally different exams to measure blood sugar levels, however essentially the most definitive test for diabetes is the hemoglobin A1C Test.

    * Often consume a wholesome diet. A weight-reduction plan low in carbohydrates is commonly prescribed for sufferers with high danger for diabetes. The logic is fairly simple, carbohydrates is broken down into glucose or sugar. Excessive risk individuals ought to eat more of green leafy greens, poultry meat moderately than crimson meat, fish, and excessive fiber breads.

    * Train regularly. Train helps in using sugar within the physique and prevents them from accumulating within the blood. It additionally helps in stimulating insulin sensitivity so the cells can successfully use sugar for vitality production.

    * Lose Weight. If your weight is above regular, it’s time to shed some pounds. Have interaction your self in a weight administration program.

    * Avoid unhealthy habits. Alcoholism, smoking, and medicines can worsen your risk factor for diabetes. These unhealthy habits will assist in buying diabetes faster.

If you’re constantly watching out for your blood sugar levels and doing every thing to keep it within normal ranges, you will not have any problem on reversing diabetes. Danger factors simply mean that you’ve more chances of having the disease. It doesn’t suggest that you have already got the illness, and you continue to can do one thing about it.

So when does diabetes turn out to be irreversible? If you begin to feel any of the signs and signs of diabetes like elevated thirst, increased urination, weight reduction, weak spot, fatigue, numbness or tingling sensations in the arms and feet, blurring of vision, and skin dryness, that’s the time. Do not forget that diabetes is an incurable disease. So, do not look forward to diabetes to become irreversible. Reverse it once you a can.

 

This post is written by Jesse Green 14.

by seph

Lean About Artificial Sweeteners For Diabetics

8:05 am in Weight Problems by seph

The food sector has come up with a solution for people on diets or with diabetes that have a sweet tooth.  They are recognized as artificial sweeteners and they may be utilised in every thing from chewing gum, coffee sweeteners, and also baking.  There is some controversy over the use of them as some of them are completely synthetic and other individuals are derived from the actual sugar plant.  But to a diabetic who does not desire to give up on their preferred pop or chewing gum they can be a life-saver. You can find also numerous diabetic cookie recipes obtainable.

The four different types of artificial sweeteners are:  saccharin, aspartame, sucralose, acesulfame potassium.  Each and every of these sorts may be found under a variety of item names and brands. Not all are created the identical way and they have distinct makes use of.  Some you are able to get in liquid or powdered form for baking wants and other individuals like aspartame is only found in foods which you obtain pre-made.

The use of these artificial sweeteners will not raise blood sugar and are safe for a diabetic to utilize.  Care and attention is still necessary because the food items you put sugar in or on most most likely will have an impact on your blood sugar.  Nevertheless adhere to your diabetic diet but use some artificial sweeteners to make it just a little sweeter.

Some diabetics may possibly desire to use honey as a substitute for sugar.  You definitely can make this substitution, nevertheless, honey is extremely comparable to sugar in carbohydrate content and also the effects it’s going to have on your blood glucose level.  It really is best to appreciate honey in small moderations if at all.

Aspartame has been linked in some medical research with Alzheimer’s disease.  Speak for your doctor about the benefits and risks of utilizing any in the artificial sweeteners if you have any issues about the prospective well being risks.